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Published on: February 18, 2015
International Workshop on Oral and Gastrointestinal Candidosis: From Pathology to Therapy. Introduction
Abstract:
Oral candidosis is the manifestation of candidosis earliest described. In fact pertinent cases are already to be found in the corpus hippocraticum. Exactly 150 years ago a fungus was found in lesions of orogastrointestinal candidosis by the German surgeon Langenbeck. For a long time, there was much dispute on the proper term for the most important causative organism of thrush and correspondingly for the proper name of the diseases caused. Today, Candida albicans is accepted by virtually everybody and the discussion on the name of the disease only focuses on the terms candidiasis and candidosis of which the latter seems preferable. Facing the scientific progress in the field of Candida and candidosis research and the permanent change of both the causative organism and the corresponding disease in the age of the HIV-infection (AIDS), it seems rewarding to review epidemiology, microbiology, nosology and treatment of oral and gastrointestinal candidosis.
Insights
Oral candidosis, caused by Candida albicans, has a long history. This review examines the epidemiology, microbiology, and treatment of oral and gastrointestinal candidosis, especially in the context of HIV infection.
Area of Science:
- Medical Mycology
- Infectious Diseases
Background:
- Oral candidosis is the earliest described manifestation of candidosis, with historical records dating back to Hippocrates.
- The causative agent, Candida albicans, was identified 150 years ago, though nomenclature debates persisted.
- The field of Candida and candidosis research has seen significant scientific progress.
Purpose of the Study:
- To review the epidemiology, microbiology, nosology, and treatment of oral and gastrointestinal candidosis.
- To address the evolving understanding of Candida and candidosis, particularly in the context of HIV infection (AIDS).
Main Methods:
- Literature review focusing on historical and current research in oral and gastrointestinal candidosis.
- Analysis of scientific progress in Candida and candidosis research.
- Examination of changes in causative organisms and disease presentation.
Main Results:
- Candida albicans is the widely accepted causative organism for thrush.
- Candidosis remains a significant oral and gastrointestinal infection.
- HIV infection (AIDS) has influenced the presentation and understanding of candidosis.
Conclusions:
- Candidosis research continues to evolve, necessitating updated reviews.
- Understanding the epidemiology, microbiology, and treatment is crucial for managing oral and gastrointestinal candidosis.
- The term 'candidosis' is preferred over 'candidiasis'.
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