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Serum Vitamin D Levels in Patients with Acute Anterior Uveitis
Zeynep Dadaci1, Servet Cetinkaya2, Nursen Oncel Acir1
1a Mevlana University School of Medicine , Department of Ophthalmology , Konya , Turkey.
Purpose:
To evaluate serum 25-hydroxyvitamin D levels in patients with acute anterior uveitis (AAU).
Methods:
This observational case-control study involved 20 patients with AAU, and 20 consecutive, age and sex-matched healthy subjects without any ocular or systemic diseases. Serum 25-hydroxyvitamin D was quantified with electrochemiluminescence technique.
Results:
No significant differences were found between the groups with respect to age (p = 0.185) and sex (p = 0.465). Serum vitamin D levels of the subjects with AAU (mean 5.75 ± 4.50 ng/mL, median 4.00 ng/mL, range: 3.00-19.00 ng/mL) were significantly lower than the control group (mean 12.96 ± 5.89 ng/mL, median 11.00 ng/mL, range: 5.20-25.92 ng/mL) (p<0.001).
Conclusions:
We found significantly low serum levels of vitamin D in patients with AAU, which suggest that vitamin D deficiency may play a role in the pathogenesis of anterior uveitis. Further studies are necessary to demonstrate the efficacy of vitamin D supplementation in the management of patients with anterior uveitis.
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