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Updated: Mar 23, 2026
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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
762
Pulse pressure can predict mortality in advanced heart failure.
Ana Rita Ferreira1, Sofia Mendes1, Luís Leite1
1Serviço de Cardiologia A, Centro Hospitalar e Universitário de Coimbra, Hospitais da Universidade de Coimbra, Coimbra, Portugal.
Summary
Pulse pressure (PP) can predict cardiovascular death in advanced heart failure patients. Lower PP (≤40 mmHg) was associated with increased mortality and greater left ventricular dysfunction in this patient group.
Area of Science:
- Cardiology
- Clinical Medicine
- Biomedical Engineering
Background:
- Pulse pressure (PP), the difference between systolic and diastolic blood pressure, increases with age.
- Elevated PP is a known risk factor for coronary heart disease and heart failure.
- The prognostic value of PP in advanced heart failure requires further investigation.
Purpose of the Study:
- To determine if pulse pressure (PP) can serve as a prognostic marker in patients with advanced heart failure.
- To assess the association between PP and cardiovascular outcomes in this population.
Main Methods:
- Retrospective study of 914 patients with NYHA class III-IV heart failure.
- Patients were categorized into two groups based on admission PP: >40 mmHg (Group 1) and ≤40 mmHg (Group 2).
- Follow-up for cardiovascular death and heart transplantation over a median of 666 days.
Main Results:
- Group 2 (PP ≤40 mmHg) exhibited significantly higher mortality compared to Group 1 (PP >40 mmHg) (log-rank p=0.002).
- Left ventricular dysfunction was more pronounced in patients with lower pulse pressure (Group 2).
Conclusions:
- Pulse pressure is a readily calculable and valuable prognostic marker for cardiovascular death in advanced heart failure.
- Lower pulse pressure may indicate more severe left ventricular dysfunction and a poorer prognosis.
Keywords:
Disfunção ventricular esquerdaHeart failureInsuficiência cardíacaLeft ventricular dysfunctionPressão de pulsoPulse pressureMore Related Videos
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