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Updated: Mar 23, 2026

A Rehabilitation Program of Exoskeleton-assisted Body Weight-Supported Treadmill Training with Non-immersive Virtual Reality for Stroke Patients
Published on: May 16, 2025
Physical fitness training for stroke patients
David H Saunders1, Mark Sanderson, Sara Hayes
1Moray House School of Education, Institute for Sport, Physical Education and Health Sciences (SPEHS), University of Edinburgh, St Leonards Land, Holyrood Road, Edinburgh, Midlothian, UK, EH8 2AZ.
Physical fitness training, including cardiorespiratory and mixed training, can reduce disability after stroke by improving mobility and walking. Resistance training is not supported by current evidence, and more research is needed on long-term effects and cognitive function.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Exercise Physiology
Background:
- Physical fitness levels are often low in stroke survivors, impacting recovery and daily function.
- The effectiveness of physical fitness interventions in reducing post-stroke disability remains unclear.
Purpose of the Study:
- To evaluate the impact of cardiorespiratory and resistance training on death, dependence, and disability in stroke survivors.
- To assess training effects on adverse events, risk factors, physical fitness, mobility, function, quality of life, mood, and cognitive function.
Main Methods:
- A systematic review and meta-analysis of randomized controlled trials comparing exercise interventions with usual care or non-exercise interventions.
- Searched multiple databases up to February 2015, including ongoing trials and expert consultations.
- Included 58 trials with 2797 participants, analyzing cardiorespiratory, resistance, and mixed training interventions.
Main Results:
- Cardiorespiratory and mixed training showed moderate to small improvements in global disability indices.
- Cardiorespiratory training significantly improved walking speed and capacity.
- Mixed training also enhanced walking speed and capacity, with slight improvements in balance; resistance training effects were inconclusive.
Conclusions:
- Cardiorespiratory and mixed training are recommended for post-stroke rehabilitation to enhance walking and mobility.
- Evidence for resistance training is insufficient.
- Long-term effects, impact on death/dependence, and cognitive function require further investigation.
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