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Proteomics

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...

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Updated: Mar 23, 2026

A Practical Guide to Phylogenetics for Nonexperts

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

UniProt Tools.

Sangya Pundir¹, Maria J Martin¹, Claire O'Donovan¹

¹European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Cambridge, United Kingdom.

Current Protocols in Bioinformatics

|March 25, 2016

Summary

This summary is machine-generated.

The Universal Protein Resource (UniProt) offers vital protein sequence and annotation data through its website, providing essential tools for researchers. It facilitates sequence similarity searching, multiple sequence alignment, and identifier mapping for protein data access and conversion.

Keywords:

UniProt navigation search tutorial

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Area of Science:

Bioinformatics
Proteomics
Computational Biology

Background:

The Universal Protein Resource (UniProt) is a critical database for protein information.
UniProt provides extensive protein sequence and annotation data to the scientific community.
The UniProt website is a highly visited resource, indicating its importance for researchers.

Purpose of the Study:

To outline protocols for utilizing the primary tools offered by the Universal Protein Resource (UniProt).
To guide users in accessing and manipulating protein data through UniProt's web interface and tools.

Main Methods:

The study focuses on practical protocols for using UniProt's core functionalities.
Key tools covered include BLAST for sequence similarity, Align for multiple sequence alignment, and Retrieve/ID Mapping for data retrieval and conversion.
The unit details basic, alternate, and support protocols for effective tool usage.

Main Results:

UniProt provides essential tools for sequence analysis and data management.
Researchers can efficiently search for similar protein sequences using BLAST.
Multiple sequence alignments and identifier mapping are streamlined through UniProt's Align and Retrieve/ID Mapping tools.

Conclusions:

The Universal Protein Resource (UniProt) is an indispensable tool for protein research.
Effective utilization of UniProt's tools enhances data retrieval and analysis capabilities.
This guide provides practical methods for leveraging UniProt for bioinformatics and proteomics research.