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Related Concept Videos

Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

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The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
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Related Experiment Video

Updated: Mar 23, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

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Primary Intraosseous Meningioma.

Thomas C Chen1

  • 1Neurosurgery and Pathology, University of Southern California, 1200, N state st suite 3300, Los Angeles, CA 90033, USA.

Neurosurgery Clinics of North America
|March 26, 2016
PubMed
Summary

Primary intraosseous meningiomas, tumors within skull bones, are rare extradural meningiomas. This review summarizes existing literature on their classification, diagnosis, and surgical treatment.

Area of Science:

  • Neurosurgery
  • Oncology
  • Pathology

Background:

  • Primary intraosseous meningiomas (PIOMs) are a rare subtype of primary extradural meningiomas, constituting approximately two-thirds of extradural cases and less than 2% of all meningiomas.
  • These tumors originate within the cranial bones, presenting unique clinical and radiographic features distinct from intradural meningiomas.

Purpose of the Study:

  • To review and summarize the existing literature on primary intraosseous meningiomas.
  • To consolidate information on classification, clinical presentation, diagnosis, and treatment of PIOMs.

Main Methods:

  • Comprehensive literature search of case reports and case series concerning primary intraosseous meningiomas.
  • Review and synthesis of data regarding tumor location, histopathology, clinical findings, diagnostic imaging, and treatment outcomes.
Keywords:
Arachnoid cellsExtradural meningiomaIntraosseous meningiomaSurgical resection

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Main Results:

  • PIOMs are classified by location and histopathology.
  • Surgical resection with wide margins is the primary treatment modality.
  • Limited data exists on the efficacy of adjuvant therapies for PIOMs.

Conclusions:

  • Primary intraosseous meningiomas require specific diagnostic and treatment considerations due to their unique origin and presentation.
  • Further research is needed to establish optimal management strategies, particularly regarding adjuvant therapies.