Testosterone and Cardiovascular Disease
Amos Tambo1, Mohsin H K Roshan1, Nikolai P Pace2
1Department of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta- Msida, Malta.
The Open Cardiovascular Medicine Journal
|March 26, 2016
Summary
Low testosterone (hypotestosteronaemia) is an emerging risk factor for cardiovascular disease (CVD). This review examines testosterone's role in heart health and its implications for cardiovascular pathology.
Area of Science:
- Cardiovascular medicine
- Endocrinology
- Pathophysiology
Background:
- Cardiovascular disease (CVD) is a major global health concern, causing over 31% of deaths worldwide.
- Atherosclerosis is the primary underlying cause of most CVDs.
- Emerging risk factors for CVD, such as hypotestosteronaemia, are increasingly recognized.
Purpose of the Study:
- To review the role of testosterone in cardiovascular health and disease.
- To explore the actions of testosterone on the cardiac vasculature.
- To discuss the implications of testosterone in cardiovascular pathology.
Main Methods:
- Literature review of epidemiological studies and scientific literature.
- Analysis of the role of testosterone in cardiovascular physiology and pathology.
- Examination of testosterone's effects on cardiac vasculature.
Main Results:
- Testosterone, once confined to reproductive biology, plays a critical role in the cardiovascular system.
- Hypotestosteronaemia is associated with an increased risk of CVD.
- Testosterone influences cardiac vasculature and contributes to cardiovascular pathology.
Conclusions:
- Testosterone is a significant factor in cardiovascular health and disease.
- Understanding testosterone's actions is crucial for managing CVD risk.
- Further research into testosterone's cardiovascular implications is warranted.
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