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Updated: Mar 23, 2026

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
The Diffuse Sclerosing Variant of Papillary Thyroid Cancer Presenting as Innumerable Diffuse Microcalcifications in
Sun Hye Jeong1, Hyun Sook Hong, Eun Hye Lee
1From the Department of Radiology (EHL, SHJ, HSH), Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Republic of Korea; and Department of Pathology (JJK), Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Republic of Korea.
Abstract:
Hashimoto's thyroiditis is the most common diffuse thyroid disease and is characterized by diffuse lymphocytic infiltration. However, the ultrasonographic findings of papillary thyroid carcinomas that arise from Hashimoto's thyroiditis in the pediatric and adolescent population are not well known.We report a rare ultrasonographic finding in a 22-year-old woman diagnosed with the diffuse sclerosing variant of papillary thyroid carcinoma that arose from underlying Hashimoto's thyroiditis: innumerable diffuse microcalcifications instead of a typical malignant-appearing nodule.
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