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Related Concept Videos

Types of Step-Growth Polymers: Polyesters01:20

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The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the polymer...
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Updated: Mar 23, 2026

Polytetrafluoroethylene PTFE as a Suture Material in Tendon Surgery
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FiberSecure suture compared to braided polyester suture.

Alan J Melvin1, Alan S Litsky2, Natalia Juncosa-Melvin1

  • 1Surgical Energetics LLC, Covington, Kentucky.

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
|March 27, 2016
PubMed
Summary
This summary is machine-generated.

FiberSecure™ suture demonstrated comparable wound strength to Mersilene, with both meeting or exceeding native tissue strength by 90 days. FiberSecure™ showed improved tissue integrity at the suture site compared to Mersilene.

Keywords:
fixationmusclepolymersuturewound closure

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Area of Science:

  • Biomaterials Science
  • Surgical Innovation
  • Tissue Engineering

Background:

  • Conventional sutures are limited by tissue tensile strength, not material strength.
  • A novel suture, FiberSecure™, was developed to overcome tissue limitations in wound closure.
  • Assessing new biomaterials is crucial for advancing surgical techniques.

Purpose of the Study:

  • To compare the mechanical and histological performance of FiberSecure™ suture against braided polyester (Mersilene) suture.
  • To evaluate suture performance in abdominal muscle incisions in a preclinical model.
  • To determine if FiberSecure™ surpasses conventional suture limitations in wound healing.

Main Methods:

  • Miniature swine underwent abdominal muscle incisions closed with either FiberSecure™ or Mersilene sutures (size 0).
  • Specimens were analyzed at 90 days post-surgery using destructive tensile testing and histology.
  • Mechanical properties (peak force, peak stress) were quantified and compared between suture groups.

Main Results:

  • FiberSecure™ group: Muscle tearing occurred away from the suture site; wound strength met or exceeded native tissue strength (Peak Force: 55.7 ± 22.1 N, Peak Stress: 579.0 ± 159.2 KPa).
  • Mersilene group: Some samples tore at the suture site; wound strength was similar to surrounding tissue (Peak Force: 51.8 ± 21.7 N, Peak Stress: 550.3 ± 239.4 KPa).
  • No significant difference in peak force or stress was observed between FiberSecure™ and Mersilene groups (p > 0.05).

Conclusions:

  • Both FiberSecure™ and Mersilene sutures achieved wound closure strength comparable to native tissue by 90 days.
  • FiberSecure™ exhibited superior performance by minimizing suture site tearing compared to Mersilene.
  • The study suggests FiberSecure™ has potential for wound closure applications where tissue strength is a limiting factor.