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Published on: November 6, 2019
Is it safe to perform adenotonsillectomy in children with Down syndrome?
Ali Cemal Yumusakhuylu1,2, Adem Binnetoglu3, Berat Demir4
1Department of Otorhinolaryngology-Head and Neck Surgery, Marmara University Faculty of Medicine, Istanbul, Turkey. dralicemal@yahoo.com.
Insights
Adenotonsillectomy is a beneficial surgery for children with Down syndrome, primarily for obstructive sleep apnea. While generally safe, potential risks like bradycardia and bleeding require careful management in specialized centers.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Genetics
Background:
- Down syndrome is associated with craniofacial abnormalities that can lead to airway obstruction.
- Adenotonsillar hypertrophy is a common cause of obstructive sleep apnea in children, particularly those with Down syndrome.
Purpose of the Study:
- To evaluate the postoperative morbidity and mortality associated with adenotonsillectomy in patients with Down syndrome.
- To identify specific complications and their management in this patient population.
Main Methods:
- A retrospective review of 30 patients with Down syndrome who underwent adenotonsillectomy between June 2012 and December 2015.
- Data collected included patient demographics, surgical indications, operative procedures, hospital stay, and postoperative complications.
Main Results:
- The majority of patients (76.6%) underwent surgery for obstructive tonsillar and adenoid hypertrophy.
- Anesthetic complications (bradycardia, respiratory difficulty) occurred in 6.6% of patients, with one requiring ICU stay and pacemaker implantation.
- Late-onset hemorrhage occurred in 10% of patients, necessitating bleeding control.
Conclusions:
- Adenotonsillectomy is a valuable procedure for managing airway obstruction in Down syndrome patients.
- While associated with certain risks, these complications are manageable in tertiary referral centers equipped to handle potential issues.
Abstract:
This retrospective review aims to evaluate the postoperative morbidity and mortality of 30 patients with Down syndrome who underwent adenotonsillectomy between June 2012 and December 2015 in a tertiary referral center. Mean age was 7.8 with a range of 3-12. There were 20 (66.6 %) male and ten (33.3 %) female patients. Mean follow-up was 23 months with a range of 7-43 months. 23 (76.6 %) of 30 patients had been operated due to obstructive tonsillar and adenoid hypertrophy, whereas seven (23.3 %) of them operated for chronic recurrent infections. All of the patients had undergone adenotonsillectomy operation; one patient had also bilateral tympanostomy tube insertion. Hospital stay was noted 1.3 days in average with a range of 1-3 days. Anesthetic complications of persistent bradycardia and postextubation respiratory difficulty occurred in two (6.6) patients. Patient who had intraoperative bradycardia necessitated intensive care unit stay and pacemaker implantation during follow-up. 3 (10 %) patients had late onset hemorrhage between days 7 and 10 and required intraoperative bleeding control. We did not experience any other morbidity and mortality except the abovementioned ones. In conclusion, adenotonsillectomy in patients with Down syndrome is a worthwhile operation with certain risks and these operations should better be performed by the tertiary referral centers which have the capacity to deal with the complications.
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