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Updated: Mar 23, 2026

Cell Type-specific Gene Expression Profiling in the Mouse Liver
Published on: September 17, 2019
Role of microRNA in liver regeneration
Peng-Sheng Yi1, Ming Zhang, Ming-Qing Xu
1Department of Liver and Vascular Surgery, West China Hospital, Sichuan University, Chengdu 610041, China. xumingqing0018@163.com.
Background:
Liver regeneration is a complex process. microRNAs (miRNAs) are short, single-stranded RNAs that modify gene expression at the post-transcriptional level. Recent investigations have revealed that miRNAs are closely linked to liver regeneration.
Data Sources:
All included studies were obtained from PubMed, Embase, the ScienceDirect databases and Web of Science, with no limitation on publication year. Only studies published in English were considered.
Results:
We grouped studies that involved miRNA and liver regeneration into two groups: miRNAs as promoters and as inhibitors of liver regeneration. We summarized the relevant miRNAs separately from the related pathways.
Conclusions:
Blocking or stimulating the pathways of miRNAs in liver regeneration may be novel therapeutic strategies in future regeneration-related liver managements. We may discover additional chemotherapy targets of miRNA.
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