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[Guillain-Barré syndrome with preserved reflexes]
G Zouiri1, R Abilkassem1, A Zerhouni2
1Service de pédiatrie, hôpital militaire d'instruction Mohammed V, Hay Riyad, Rabat, Maroc.
Summary
Guillain-Barré syndrome, a rare autoimmune disorder, can manifest as acute motor axonal neuropathy (AMAN) in children. Prompt treatment with IV immunoglobulins led to full recovery in a pediatric AMAN case.
Area of Science:
- Neurology
- Immunology
- Pediatrics
Background:
- Guillain-Barré syndrome is a rare autoimmune disorder affecting the peripheral nervous system.
- It can occur at any age, including infancy and childhood.
- Acute motor axonal neuropathy (AMAN) is a specific clinical form of Guillain-Barré syndrome.
Observation:
- A 2.5-year-old child presented with acute flaccid paralysis but preserved reflexes.
- Diagnostic investigations confirmed Guillain-Barré syndrome in its AMAN form.
Findings:
- Treatment with intravenous immunoglobulins (IVIg) resulted in complete resolution of paralysis.
- The child experienced full motor recovery following IVIg therapy.
Implications:
- The AMAN form of Guillain-Barré syndrome should be considered in pediatric cases of acute flaccid paralysis with preserved reflexes.
- Early diagnosis and treatment with IVIg can lead to favorable outcomes in pediatric AMAN.
- This case highlights the importance of recognizing diverse clinical presentations of Guillain-Barré syndrome in children.
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