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[PLACE REMAXOL AS A HEPATOPROTECTOR IN INTENSIVE THERAPY OF PERVASIVE PERITONITIS]
Anesteziologiia I Reanimatologiia
|March 31, 2016
Summary
Remaxol effectively treated pervasive peritonitis by improving hemodynamics and reducing metabolic disorders. This led to shorter respiratory support and earlier nutritional intake, demonstrating its therapeutic benefits.
Area of Science:
- Critical care medicine
- Pharmacology
- Gastroenterology
Context:
- Peritonitis is a severe condition requiring intensive management.
- Early and effective treatment is crucial for patient outcomes.
- Hepatic dysfunction and endotoxemia are common complications.
Purpose:
- To evaluate the efficacy of Remaxol in patients with pervasive peritonitis.
- To assess Remaxol's impact on metabolic disorders, endotoxemia, and hepatic dysfunction.
- To determine Remaxol's effect on systemic hemodynamics and oxygen transport.
Summary:
- Remaxol infusion (800 mg/day for 7 days) was administered to 21 peritonitis patients.
- Compared to a control group, Remaxol patients showed faster relief of metabolic disorders and endotoxemia.
- Earlier stabilization of hemodynamics and oxygen transport was observed in the Remaxol group.
Impact:
- Remaxol use resulted in reduced duration of respiratory and vasopressor support.
- Early initiation of parenteral nutrition was facilitated by Remaxol treatment.
- The study highlights Remaxol's role in managing hepatic dysfunction and preventing liver toxicity in peritonitis.
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