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[PREEMPTIVE ANALGESIA AS PART OF MULTICOMPONENT ANESTHESIA IN CHILDREN WITH OPERATIONS IN THE NASAL CAVITY AND

E V Ivlev, E A Bojko, E A Ruban

    Anesteziologiia I Reanimatologiia
    |March 31, 2016
    PubMed

    Insights

    Pre-emptive analgesia using lidocaine and paracetamol significantly reduced postoperative pain and cortisol levels in children undergoing nasal surgery. This approach also led to faster recovery and extubation times compared to fentanyl.

    Area of Science:

    • Anesthesiology
    • Pediatric Surgery
    • Pain Management

    Context:

    • Postoperative pain management in pediatric patients undergoing nasal and nasopharyngeal surgery is crucial for recovery.
    • Current analgesic strategies often involve opioids, which can have side effects.
    • Exploring non-opioid, pre-emptive analgesia offers a potential alternative for improved outcomes.

    Purpose:

    • To assess the efficacy of pre-emptive analgesia with lidocaine and paracetamol versus fentanyl for managing postoperative pain in pediatric patients.
    • To compare the incidence and severity of pain, cortisol levels, and time to extubation/transfer to the general department between the two groups.

    Summary:

    • A study involving 150 pediatric patients (3-17 years) undergoing nasal/nasopharyngeal surgery compared pre-emptive lidocaine/paracetamol with fentanyl.
    • The lidocaine/paracetamol group showed a 28% reduction in pain incidence and 50% reduction in pain severity, with lower cortisol levels.
    • This group also required 15% less additional analgesia and experienced 40-50% faster extubation and transfer to the general department.

    Impact:

    • Pre-emptive analgesia with lidocaine and paracetamol demonstrates superior pain control and faster recovery in pediatric patients compared to fentanyl.
    • This multimodal approach may reduce opioid requirements and associated adverse effects.
    • Findings support the use of lidocaine and paracetamol as a valuable strategy for enhanced recovery after nasal and nasopharyngeal surgery in children.
    Abstract

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