The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori
Ilaria M Saracino1, Cristina Zaccaro2, Giovanna Lo Re3
1First Medical Clinic, University of Bologna, Bologna 40121, Italy. iliaria.saracino@unibo.it.
Abstract:
We investigated the effects of two novel copper-based inorganic formulations for their activity against 60 isolates of Helicobacter pylori (Hp). The two copper-based formulations were tested against three NCTC Helicobacter pylori isolates and 57 clinical strains isolated from the UK and Italy in time-kill assays. Both copper-based formulations were bio-cidal against all Helicobacter pylori strains tested reducing the viable count by 4-5 log within 2 h. These two copper-based anti-microbial agents deserve further study in relation to the treatment of H. pylori-related gastric disease.
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