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Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
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Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors

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Viral arthritis.

Michael Marks1, Jonathan L Marks2

  • 1Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK, and The Hospital for Tropical Diseases, London, UK.

Clinical Medicine (London, England)
|April 3, 2016
PubMed
Summary
This summary is machine-generated.

Viral infections cause about 1% of acute arthritis cases. Identifying the specific virus through clinical, epidemiological, and serological data is crucial for diagnosis and treatment, especially with evolving viral patterns.

Keywords:
Arthritisalphavirusarthralgiahepatitisparvovirus B19

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Area of Science:

  • Rheumatology
  • Virology
  • Infectious Diseases

Background:

  • Acute-onset arthritis is a frequent clinical presentation.
  • Viral infections are an under-recognized cause of acute arthritis, accounting for approximately 1% of cases.
  • The epidemiology of viral arthritis is dynamic, influenced by vaccination and the spread of vector-borne viruses.

Purpose of the Study:

  • To review the evolving epidemiology of acute viral arthritis.
  • To highlight key viral etiologies and diagnostic considerations.
  • To emphasize the importance of a comprehensive clinical approach.

Main Methods:

  • Review of current literature on viral arthritis.
  • Analysis of epidemiological trends and common viral culprits.
  • Discussion of diagnostic strategies including serological testing.

Main Results:

  • Key viral causes include parvovirus B19, hepatitis B and C, HIV, and alphaviruses.
  • Travel history is essential for assessing risk.
  • Low-titre autoantibodies can be present in viral arthritis, complicating diagnosis.

Conclusions:

  • Accurate diagnosis requires integrating epidemiological, clinical, and serological findings.
  • While often self-limiting, some viral arthritides necessitate specific antiviral treatment.
  • Awareness of evolving viral patterns is critical for effective patient management.