Related Experiment Video
Updated: Mar 23, 2026

Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
Published on: April 24, 2016
Hyposalivation and Xerostomia: Etiology, Complications, and Medical Management
1Mount Sinai Beth Israel/Jacobi/Einstein Oral and Maxillofacial Surgery, Institute of Head and Neck and Thyroid Cancer, 10 Union Square East, Suite 5B New York, NY 10003, USA.
Abstract:
Saliva is one of the most versatile, multifunctional substances produced by the body and has a critical role in the preservation of the oropharyngeal health. It comprises a serous and mucinous component and is secreted by the major salivary glands. The mucins in the saliva serve to protect and lubricate the hard and soft tissues of the mouth, protecting them from chemical and mechanical damage. Hyposalivation can be managed by various salivary substitutes, peripheral sialagogues, and central sialagogues.
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