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Updated: Mar 23, 2026

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Medications to Assist in Tobacco Cessation for Dental Patients
Joshua M Levy1, Shelly Abramowicz2
1Division of Oral and Maxillofacial Surgery, Department of Surgery, Emory University School of Medicine, 1365 Clifton Road, Suite 2300, Building B, Atlanta, GA 30322, USA.
Abstract:
Smoking is the leading cause of preventable illness in the United States. Without assistance, only 3% to 6% of smokers successfully quit after 1 year. Nicotine replacement therapy (NRT), buproprion, and varenicline are first-line pharmacologic therapies. These medications function by reducing nicotine withdrawal symptoms and the desire to smoke. When first-line therapy does not lead to successful smoking cessation, combinations of varenicline with NRT, buproprion with NRT, and varenicline with buproprion may be efficacious. Behavioral therapy also plays a role in smoking cessation and the combination of pharmacologic therapy with behavioral therapy is more effective than either therapy alone.
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