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Related Concept Videos

Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
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Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Satellite Stem Cells and Muscular Dystrophy01:21

Satellite Stem Cells and Muscular Dystrophy

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Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
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Myocarditis I: Introduction01:21

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Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
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Myasthenia Gravis: Overview and Treatment

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Related Experiment Video

Updated: Mar 23, 2026

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
09:01

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach

Published on: June 5, 2010

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MYOSITIS OSSIFICANS PROGRESSIVA: CASE REPORT.

Frederico Barra de Moraes1, Alano Ribeiro de Queiroz Filho2, Leonardo Jorge da Silva2

  • 1Substitute Assistant Professor of Orthopedics in the Department of Orthopedics and Traumatology, Clinical Hospital of the Federal University of Goiás, Goiãnia, GO, Brazil.

Revista Brasileira De Ortopedia
|April 5, 2016
PubMed
Summary

Myositis ossificans progressiva, a rare genetic disorder, causes progressive calcification and mobility loss. This case study explores its clinical features and available treatments like ascorbic acid and bisphosphonates.

Keywords:
Ascorbic AcidBisphosphonatesMyositis OssificansOssification, Heterotopic

Related Experiment Videos

Last Updated: Mar 23, 2026

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
09:01

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach

Published on: June 5, 2010

14.7K

Area of Science:

  • Medical Genetics
  • Rheumatology
  • Orthopedics

Background:

  • Myositis ossificans progressiva (MOP) is a rare, autosomal dominant inherited disorder.
  • Characterized by progressive heterotopic ossification of skeletal muscles and connective tissues.
  • Fewer than 1,000 cases reported globally, highlighting its rarity.

Observation:

  • Patients present with inflammatory edema leading to progressive calcification.
  • Significant loss of mobility in affected body regions is a hallmark.
  • This study details a specific case of MOP.

Findings:

  • Clinical manifestations of MOP were systematically described.
  • The study reviewed current treatment options for MOP.
  • Oral ascorbic acid and intravenous bisphosphonates were discussed as therapeutic interventions.

Implications:

  • Improved understanding of MOP's clinical presentation.
  • Discussion of therapeutic strategies may guide future MOP management.
  • Highlights the need for further research into effective MOP treatments.