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Updated: Mar 23, 2026

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Ethical Considerations of Whole-Eye Transplantation
Wesley N Sivak1, Edward H Davidson1, Chiaki Komatsu1
1University of Pittsburgh Medical Center, Department of Plastic Surgery, Pittsburgh, Pennsylvania USA.
Abstract:
Whole eye transplantation (WET) remains experimental. Long presumed impossible, recent scientific advances regarding WET suggest that it may become a clinical reality. However, the ethical implications of WET as an experimental therapeutic strategy remain largely unexplored. This article evaluates the ethical considerations surrounding WET as an emerging experimental treatment for vision loss. A thorough review of published literature pertaining to WET was performed; ethical issues were identified during review of the articles.
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