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Related Concept Videos

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Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Related Experiment Video

Updated: Mar 2, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
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Cervicofacial Botryomycosis: Is Atopic Dermatitis a Predisposing Factor?

Markus Vincent Heppt1, Jivko Kamarashev2

  • 1Department of Dermatology and Allergy, Ludwig Maximilian University, Munich, Germany.

Dermatopathology (Basel, Switzerland)
|April 6, 2016
PubMed
Summary

Botryomycosis, a rare skin infection, can present in the head and neck. Atopic dermatitis may be a predisposing factor, with characteristic histologic findings and potential for relapse after antibiotic treatment.

Keywords:
Atopic dermatitisAtopic eczemaBotryomycosisGranulomaImmunocompromised patientImmunodeficiencyPyodermaStaphylococcus aureus

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Microbiology

Background:

  • Botryomycosis is a rare bacterial infection typically affecting the skin.
  • Disease development is influenced by bacterial virulence and host immune status.

Observation:

  • A case of cervicofacial botryomycosis in a 47-year-old male with atopic dermatitis is presented.
  • The patient exhibited painful, suppurative nodules on the head and neck.
  • Skin biopsy revealed pathognomonic features of botryomycosis: Gram-positive bacterial colonies with an eosinophilic rim.

Findings:

  • Lesions showed a good initial response to systemic antibiotics.
  • Recurrence of lesions was observed upon treatment cessation.
  • Histologic examination confirmed characteristic botryomycosis features.

Implications:

  • This case highlights the diagnostic histologic features of botryomycosis.
  • Atopic dermatitis is suggested as a potential predisposing factor for this rare infection.
  • Understanding predisposing factors is crucial for managing recurrent botryomycosis.