Related Experiment Video

Updated: Mar 23, 2026

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
04:48

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery

Published on: November 28, 2018

8.4K

Echocardiographic predictors of outcomes in adults with aortic stenosis

Romain Capoulade1, Florent Le Ven1, Marie-Annick Clavel1

  • 1Institut Universitaire de Cardiologie et de Pneumologie de Québec/Québec Heart & Lung Institute, Laval University, Québec City, Québec, Canada.

Heart (British Cardiac Society)
|April 7, 2016
PubMed

Insights

Echocardiographic parameters of left ventricular (LV) systolic function, specifically LV ejection fraction (LVEF) and stroke volume index (SVi), are key predictors of mortality in aortic stenosis (AS). Stenosis severity parameters do not predict overall mortality.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Imaging

Background:

  • Aortic stenosis (AS) is a significant cardiovascular condition.
  • Accurate prediction of mortality in AS patients is crucial for timely intervention.
  • Echocardiography plays a vital role in assessing AS severity and cardiac function.

Purpose of the Study:

  • To evaluate the predictive value of echocardiographic parameters for mortality in patients with AS.
  • To determine whether left ventricular (LV) systolic function or AS severity parameters are stronger predictors of mortality.
  • To investigate the role of LV systolic function in risk stratification for AS.

Main Methods:

  • A cohort of 1065 consecutive patients with AS was studied.
  • Patients were followed for a median of 5.7 years.
  • Outcomes included aortic valve replacement, composite events, all-cause mortality, and cardiovascular mortality.

Main Results:

  • Echocardiographic parameters of AS severity (VPeak, MG, AVA) strongly predicted valve-related events.
  • Left ventricular ejection fraction (LVEF) and stroke volume index (SVi) were the primary echocardiographic predictors of mortality.
  • After multivariable adjustment, LVEF and SVi remained significant independent predictors of mortality, while VPeak and MG did not.

Conclusions:

  • Low LVEF and low flow (low SVi) are the most powerful echocardiographic predictors of mortality in AS.
  • AS severity parameters predict valve-related events but not overall mortality.
  • Integrating low flow parameters into risk stratification and treatment decisions for AS patients is recommended.
Abstract

More Related Videos

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice12:12

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice

Published on: February 14, 2017

16.9K
Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction09:20

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

7.2K

Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
834
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
545
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
402
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.1K
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
502
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
409