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Published on: May 16, 2025
Perioperative Treatment of Patients with Rheumatoid Arthritis
Khaled J Saleh1, Alexander Kurdi, Mouhanad M El-Othmani
1Professor and Chair of the Department of Orthopaedic Surgery, Director of Clinical and Translational Research, Southern Illinois University School of Medicine, Springfield, Illinois.
Rheumatoid arthritis (RA) is an inflammatory disease causing joint damage. While medications slow progression, some patients still need surgery, requiring careful medical evaluation for better outcomes.
Area of Science:
- Rheumatology
- Immunology
- Orthopaedic Surgery
Background:
- Rheumatoid arthritis (RA) is a chronic autoimmune disease causing systemic inflammation and joint deterioration.
- RA significantly impacts quality of life, leading to pain, disability, and reduced function.
- Disease-modifying antirheumatic drugs (DMARDs) have improved RA management, reducing the need for orthopaedic interventions.
Purpose of the Study:
- To highlight the importance of understanding medical considerations in RA patients undergoing surgery.
- To emphasize the need for improved knowledge of disease- and treatment-related complications.
- To underscore how better preoperative planning can enhance postoperative outcomes in RA patients.
Main Methods:
- Literature review focusing on medical complications in rheumatoid arthritis.
- Analysis of the impact of pharmacologic treatments on surgical outcomes.
- Synthesis of information regarding preoperative assessment and planning for RA patients.
Main Results:
- Despite advances in DMARDs, a significant proportion of RA patients require surgical intervention.
- Both the autoimmune disease process and its treatments can lead to medical complications relevant to surgery.
- Comprehensive medical understanding is crucial for optimizing surgical readiness.
Conclusions:
- Improved preoperative planning and medical clearance are essential for RA patients undergoing surgery.
- Addressing disease-specific and treatment-related complications can mitigate surgical risks.
- Enhanced medical knowledge ultimately leads to better postoperative outcomes for individuals with rheumatoid arthritis.
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