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Pediatric urolithiasis: experience at a tertiary care pediatric hospital
Luana Amancio1, Maira Fedrizzi1, Nilzete Liberato Bresolin1
1Universidade Federal de Santa Catarina, Brazil.
Insights
Pediatric urolithiasis is increasingly common, often linked to metabolic issues. Early metabolic evaluation is crucial for effective treatment and preventing stone recurrence in children.
Area of Science:
- Pediatric Nephrology
- Urology
- Metabolic Disorders
Background:
- Pediatric urolithiasis incidence is rising, presenting significant morbidity and high recurrence rates.
- Idiopathic urolithiasis in children frequently indicates an underlying metabolic abnormality.
- Targeted research and interventions are vital for reducing stone formation and complications.
Purpose of the Study:
- To characterize pediatric urolithiasis patients regarding demographics and clinical presentation.
- To investigate the etiology, treatment, recurrence patterns, and outcomes in pediatric urolithiasis.
- To analyze data from a tertiary care pediatric hospital setting.
Main Methods:
- Retrospective descriptive study of 106 pediatric patients diagnosed with urolithiasis from 2002-2012.
- Data collected from medical records, confirmed by imaging and urine analysis.
- Inclusion criteria: confirmed diagnosis and available urine test results.
Main Results:
- Most patients (65%) were male, with an average age of 8.0 years; 85% had a family history of urolithiasis.
- Hypercalciuria was the most common metabolic abnormality (93.2%). Abdominal pain and renal colic were frequent symptoms.
- Treatment included medication (78%) and surgery (38%), with a 39% response rate. Recurrence affected 34.2%, and follow-up was poor (only 4.7% continued).
Conclusions:
- Detailed metabolic evaluation is essential post-initial presentation for pediatric urolithiasis.
- This evaluation aids in treatment, monitoring, and prevention of stone recurrence and complications.
- Improved patient follow-up is critical for managing pediatric urolithiasis effectively.
Introduction:
Pediatric urolithiasis has become more prevalent in recent decades, with high recurrence rates and considerable morbidity. Most children with idiopathic urolithiasis have an underlying metabolic abnormality and proper research provides therapeutic interventions to reduce the formation of new stones and its complications.
Objective:
To identify demographic and clinical characteristics of pediatric urolithiasis, etiology, treatment management, disease recurrence and patient outcomes in a tertiary care pediatric hospital.
Methods:
A retrospective descriptive study of pediatric patients admitted to the Hospital Infantil Joana de Gusmão in Florianópolis, SC, Brazil, who were diagnosed with urolithiasis, from January 2002 to December 2012. Data were obtained from medical records. Those patients with diagnosis confirmed by imaging and 24hr urine or single sample urine were included.
Results:
We evaluated 106 pediatric patients (65% M). Average age at diagnosis was 8.0 ± 4.2 and 85% of them had positive family history of urolithiasis. Abdominal pain, renal colic and urinary tract infection were the main manifestations. 93.2% had metabolic abnormality and hypercalciuria was the most common. Pharmacological treatment was established in 78% of cases. Potassium citrate and hydrochlorothiazide were used. Surgical treatment was performed in 38% of patients. There was response to treatment in 39% of patients with recurrence of urolithiasis in 34.2% of them. Only 4.7% of patients continued follow-up, 6.6% were referred to other services, 8.5% were discharged and 73.8% lost follow-up.
Conclusion:
Pediatric urolithiasis deserves a detailed metabolic evaluation after their initial presentation for treatment, monitoring and prevention of its formation and its complications.
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