Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Methods of evaluating chondroprotective treatment].

M Dougados, L Duchesne

    La Revue Du Praticien
    |March 2, 1989
    PubMed
    Summary

    Chondroprotective therapies aim to halt osteoarthritis progression by protecting articular cartilage. Evaluating their clinical benefit is complex, depending on patient factors and study design, with ongoing debate on individual versus population-based assessments.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Global health in axial spondyloarthritis: thresholds for the Assessment of SpondyloArthritis international Society Health Index and the EuroQol score: analysis of the ASAS-PerSpA study.

    Scandinavian journal of rheumatology·2024
    Same author

    Performance of cut-offs of the ASAS Health Index to discriminate between treatment groups in patients with axial spondyloarthritis in the TICOSPA trial.

    Seminars in arthritis and rheumatism·2024
    Same author

    Impact of pregnancy on sacroiliac imaging in women with axial spondyloarthritis: results of the analysis of the DESIR cohort.

    Scandinavian journal of rheumatology·2024
    Same author

    [Implementation, of multidisciplinary consultations for patients with inflammatory arthritis and treated with subcutaneous biologic DMARDs: Assessment at one year and outlook].

    Annales pharmaceutiques francaises·2022
    Same author

    Non-use of combination HIV prevention tools and its determinants among men who have sex with men living in France.

    Infectious diseases now·2022
    Same author

    The ASAS-OMERACT core domain set for axial spondyloarthritis.

    Seminars in arthritis and rheumatism·2021

    Area of Science:

    • Orthopedics and Rheumatology
    • Biomedical Science
    • Pharmacology

    Context:

    • Osteoarthritis (OA) management involves chondroprotective therapies.
    • These therapies target pathological processes in articular cartilage degradation.
    • Assessing treatment efficacy presents significant challenges.

    Purpose:

    • To explore the fundamental role of chondroprotective therapy in osteoarthritis.
    • To identify factors influencing the assessment of clinical benefit.
    • To address the debate on evaluating treatment efficacy in individual patients versus patient populations.

    Summary:

    • Chondroprotective therapies are crucial for managing osteoarthritis by inhibiting cartilage breakdown.
    • Clinical benefit assessment is complicated by patient-specific factors (e.g., OA type, location, stage) and treatment parameters (duration, criteria).
    • The optimal methodology for assessing treatment effectiveness—whether in single patients or through population studies—remains a subject of discussion.

    Impact:

    • Highlights the complexity in evaluating osteoarthritis treatments.
    • Informs future research design for chondroprotective therapy trials.
    • Aids clinicians in understanding the nuances of treatment assessment for individual patients.

    Related Experiment Videos