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Updated: Mar 23, 2026

Automated Midline Shift and Intracranial Pressure Estimation based on Brain CT Images
Published on: April 13, 2013
Craniocervical Pneumatization: Estimation of Prevalence and Imaging of Treatment Response
Courtney M Tomblinson1, Nicholas L Deep, Steven M Weindling
1*Department of Radiology†Department of Otolaryngology-Head & Neck Surgery, Mayo Clinic, Phoenix, Arizona‡Department of Radiology, Mayo Clinic, Jacksonville, Florida§Department of Radiology, Mayo Clinic, Rochester, Minnesota||Department of Medicine Services, VA Southern Nevada Healthcare System, North Las Vegas, Nevada.
Objective:
Estimate the prevalence of craniocervical pneumatization (CCP) and describe successful treatment of this condition with clinical and radiologic correlation.
Patients:
Individuals with documented CCP on computed tomography (CT).
Intervention(S):
CT scans of the head, temporal bone, face, neck, and cervical spine. Cessation of habitual Valsalva maneuver (VM) and insertion of pressure-equalization (PE) tubes.
Main Outcome Measure:
The prevalence of CCP on CT examinations performed during two decades in a large academic healthcare system. Documentation of symptomatic and imaging improvement following treatment of CCP.
Results:
Radiology database review identified two cases of CCP out of a total of 636,854 head and neck CT scans (0.00031%) or 43,553 temporal bone CT scans (0.0046%). Both CCP patients were symptomatic (aural fullness, hearing loss, vertigo) and practiced habitual VM. One patient showed decreased CCP 4 months following cessation of VM, whereas the other patient improved symptomatically and demonstrated reversion of CCP to normal bone on magnetic resonance imaging (MRI) within 3 years following PE tube placement.
Conclusions:
Acquired CCP is exceedingly rare and, when successfully treated, reversion to normal bone may accompany symptom resolution.
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