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Evaluation and treatment of hypertensive crises in children
Deborah R Stein1, Michael A Ferguson1
1Division of Nephrology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Insights
Hypertensive crises in children require prompt evaluation and treatment to prevent severe complications. Gradual blood pressure reduction is crucial to avoid cerebral ischemia, with underlying cause identification aiding therapy.
Area of Science:
- Pediatrics
- Cardiology
- Critical Care Medicine
Background:
- Hypertensive crises in children are medical emergencies.
- Prompt identification, evaluation, and treatment are vital to prevent end-organ injury and death.
- Current treatments involve continuous intravenous antihypertensive medications and intensive care unit monitoring.
Purpose of the Study:
- To highlight the critical nature of hypertensive crises in pediatric patients.
- To emphasize the need for prompt and appropriate management to prevent severe outcomes.
- To underscore the importance of gradual blood pressure reduction and consideration of underlying causes.
Main Methods:
- Review of current treatment protocols for pediatric hypertensive crises.
- Discussion of commonly used intravenous antihypertensive medications.
- Emphasis on monitoring in the intensive care unit setting.
Main Results:
- Severe hypertension in children necessitates immediate medical intervention.
- Limited pediatric-specific trials exist for evidence-based therapeutic guidance.
- Gradual blood pressure lowering is essential to prevent cerebral ischemia.
Conclusions:
- Hypertensive crises in children demand urgent and precise medical management.
- Further pediatric-specific research is needed to establish evidence-based treatment guidelines.
- Therapeutic strategies should prioritize gradual blood pressure reduction and address the root cause.
Abstract:
Hypertensive crises in children are medical emergencies that must be identified, evaluated, and treated promptly and appropriately to prevent end-organ injury and even death. Treatment in the acute setting typically includes continuous intravenous antihypertensive medications with monitoring in the intensive care unit setting. Medications commonly used to treat severe hypertension have been poorly studied in children. Dosing guidelines are available, although few pediatric-specific trials have been conducted to facilitate evidence-based therapy. Regardless of what medication is used, blood pressure should be lowered gradually to allow for accommodation of autoregulatory mechanisms and to prevent cerebral ischemia. Determining the underlying cause of the blood pressure elevation may be helpful in guiding therapy.
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Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Hypertension and Regulation of Blood Pressure

