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Related Experiment Video

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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
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Real-time three-dimensional left ventricular contraction in patients with diastolic dysfunction.

Suzan Hatipoğlu1, Gamze Babur Güler2, Özgür Kaya3

  • 1Maltepe Ersoy Hospital, Altay Çesme Mah. Varna Sok. No. 16, Maltepe, Istanbul, Turkey. suzan_hatipoglu@hotmail.com.

Journal of Medical Ultrasonics (2001)
|April 8, 2016
PubMed
Summary

Real-time three-dimensional echocardiography (3DE) assessed left ventricular (LV) myocardial function in patients with diastolic dysfunction (DD). A decline in segmental motion (excursion-SD) was observed with increasing DD grade, indicating reduced differences in segment excursion.

Keywords:
3-Dimensional echocardiographyDiastolic dysfunctionLeft ventricle

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Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Mechanics

Background:

  • Systolic alterations in left ventricular (LV) myocardial function are known in diastolic dysfunction (DD).
  • Standard 2D echocardiography has limitations in assessing global LV contraction.
  • Real-time 3D echocardiography (3DE) offers advanced capabilities for detailed myocardial function analysis.

Purpose of the Study:

  • To evaluate global 3DE LV contraction in patients with and without DD.
  • To compare LV myocardial function parameters between normal and DD groups with preserved ejection fraction (EF).
  • To investigate the utility of 3DE-derived parameters in characterizing DD.

Main Methods:

  • Sixty-five patients with normal EF (>50%) were assessed using conventional echocardiography and 3DE.
  • Key parameters measured included end-diastolic volume, end-systolic volume, EF, and segmental motion analysis (excursion-SD).
  • Patients were categorized into normal, Grade 1, and Grade 2 DD groups.

Main Results:

  • Significant differences were observed in multiple parameters, including left atrial volume, septal and posterior wall motion, and various Doppler indices, across DD grades.
  • Excursion-SD and septal measurements were statistically significant predictors of DD grade (p < 0.001).
  • A decline in excursion-SD was noted with increasing DD severity.

Conclusions:

  • Reduced excursion-SD values correlate with increased diastolic dysfunction grade.
  • 3DE-derived measurement of segmental motion differences (excursion-SD) is a valuable tool for assessing DD.
  • This study highlights the potential of 3DE in characterizing subtle changes in LV contraction associated with DD.