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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Pediatric Thromboembolism in Japan.
Kenichi Tetsuhara1,2, Akira Ishiguro3,4, Nobuaki Michihata3
1Department of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, Japan. ken-tetsuhara@mti.biglobe.ne.jp.
Thromboembolism in Japanese children is increasing, particularly in infants. Prompt detection in pediatric intensive care is crucial for better outcomes.
Area of Science:
- Pediatric Medicine
- Hematology
- Epidemiology
Background:
- Thromboembolism (TE) is a significant concern in pediatric populations.
- Understanding the clinical and epidemiological features of TE in children is essential for effective management.
Purpose of the Study:
- To investigate the clinical and epidemiologic characteristics of thromboembolism in Japanese children.
- To analyze the incidence, patient demographics, and common types of thromboembolism in this cohort.
Main Methods:
- Retrospective review of clinical data from 77 pediatric patients diagnosed with thromboembolism.
- Data collected from a national tertiary pediatric care center.
Main Results:
- The incidence of thromboembolism was 15 per 10,000 hospital admissions.
- Infants under one year old constituted the largest age group (25 patients).
- Common diagnoses included portal vein thrombosis (15), central venous catheter obstruction (13), and cerebral infarction (9).
- Eight mortalities and six significant sequelae were reported among the 77 patients.
- A trend of increasing thromboembolism occurrence was observed over the study period.
Conclusions:
- Thromboembolism poses a notable risk in pediatric care, especially in intensive care settings.
- Increased vigilance and prompt detection of thromboembolism are recommended for improved patient outcomes.
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