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Pediatric Thromboembolism in Japan

Kenichi Tetsuhara1,2, Akira Ishiguro3,4, Nobuaki Michihata3

  • 1Department of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, Japan. ken-tetsuhara@mti.biglobe.ne.jp.

Indian Journal of Pediatrics
|April 8, 2016
PubMed

Insights

Thromboembolism in Japanese children is increasing, particularly in infants. Prompt detection in pediatric intensive care is crucial for better outcomes.

Area of Science:

  • Pediatric Medicine
  • Hematology
  • Epidemiology

Background:

  • Thromboembolism (TE) is a significant concern in pediatric populations.
  • Understanding the clinical and epidemiological features of TE in children is essential for effective management.

Purpose of the Study:

  • To investigate the clinical and epidemiologic characteristics of thromboembolism in Japanese children.
  • To analyze the incidence, patient demographics, and common types of thromboembolism in this cohort.

Main Methods:

  • Retrospective review of clinical data from 77 pediatric patients diagnosed with thromboembolism.
  • Data collected from a national tertiary pediatric care center.

Main Results:

  • The incidence of thromboembolism was 15 per 10,000 hospital admissions.
  • Infants under one year old constituted the largest age group (25 patients).
  • Common diagnoses included portal vein thrombosis (15), central venous catheter obstruction (13), and cerebral infarction (9).
  • Eight mortalities and six significant sequelae were reported among the 77 patients.
  • A trend of increasing thromboembolism occurrence was observed over the study period.

Conclusions:

  • Thromboembolism poses a notable risk in pediatric care, especially in intensive care settings.
  • Increased vigilance and prompt detection of thromboembolism are recommended for improved patient outcomes.
Abstract

Keywords:
ChildrenEpidemiologyThromboembolismThrombophilia

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