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Updated: Mar 23, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Peri-procedural imaging for transcatheter mitral valve replacement
Navin Natarajan1, Parag Patel1, Thomas Bartel1
11 Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA ; 2 Department of Cardiovascular Medicine, 3 Department of Cardiothoracic Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH 44106, USA ; 4 Imaging Institute, Cleveland Clinic, Cleveland, OH 44106, USA.
Abstract:
Mitral regurgitation (MR) has a high prevalence in older patient populations of industrialized nations. Common etiologies are structural, degenerative MR and functional MR secondary to myocardial remodeling. Because of co-morbidities and associated high surgical risk, open surgical mitral repair/replacement is deferred in a significant percentage of patients. For these patients transcatheter repair/replacement are emerging as treatment options. Because of the lack of direct visualization, pre- and intra-procedural imaging is critical for these procedures. In this review, we summarize mitral valve anatomy, trans-catheter mitral valve replacement (TMVR) options, and imaging in the context of TMVR.
Insights
Mitral regurgitation (MR) affects many older adults. Transcatheter mitral valve replacement (TMVR) offers an alternative to surgery for high-risk patients, with imaging being crucial for success.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Imaging
Background:
- Mitral regurgitation (MR) is prevalent in elderly populations.
- Degenerative and functional MR are common causes.
- High surgical risk often precludes traditional open-heart surgery.
Purpose of the Study:
- To review mitral valve anatomy.
- To discuss transcatheter mitral valve replacement (TMVR) options.
- To highlight the role of imaging in TMVR.
Main Methods:
- Literature review of current TMVR techniques.
- Analysis of imaging modalities for pre- and intra-procedural guidance.
- Summary of anatomical considerations for mitral valve interventions.
Main Results:
- TMVR is an emerging alternative for high-risk MR patients.
- Accurate imaging is essential for successful TMVR outcomes.
- Various TMVR devices and techniques are available.
Conclusions:
- Transcatheter mitral valve replacement is a viable option for select patients.
- Advanced imaging is critical for patient selection and procedural success in TMVR.
- Further research into TMVR technologies and imaging is warranted.
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