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An electrochemical peptide cleavage-based biosensor for matrix metalloproteinase-2 detection with exonuclease
Ding Wang1, Yali Yuan, Yingning Zheng
1Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. yqchai@swu.edu.cn yuanruo@swu.edu.cn.
Chemical Communications (Cambridge, England)
|April 8, 2016
Abstract:
In this work, an electrochemical peptide biosensor was developed for matrix metalloproteinase-2 (MMP-2) detection by conversion of a peptide cleavage event into DNA detection with exonuclease III (Exo III)-assisted cycling signal amplification.
