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Caprine leptospirosis: Hematobiochemical and urinalyses studies
Priti Dilipsinh Vihol1, Jignesh M Patel1, Jatin H Patel2
1Department of Veterinary Pathology, Vanbandhu College of Veterinary Science and Animal Husbandry, Navsari Agricultural University, Navsari - 396 450, Gujarat, India.
Veterinary World
|April 9, 2016
Summary
Leptospirosis in goats causes significant hematobiochemical changes, indicating liver damage. These findings are crucial for effective treatment strategies in affected herds.
Area of Science:
- Veterinary Medicine
- Animal Pathology
- Infectious Diseases
Background:
- Leptospirosis is a significant zoonotic disease affecting livestock globally.
- Goats in the South Gujarat region of India are susceptible to leptospirosis.
- Understanding clinicopathological alterations is vital for disease management.
Purpose of the Study:
- To investigate clinicopathological changes in goats naturally infected with leptospirosis.
- To correlate serological status with hematobiochemical and urinalysis findings.
- To identify markers of hepatic damage in affected goats.
Main Methods:
- Collected 459 blood/serum and 292 urine samples from goats in South Gujarat.
- Performed hematobiochemical analyses and urinalyses.
- Screened serum samples for anti-leptospiral antibodies using the microscopic agglutination test (MAT).
Main Results:
- 116 out of 459 goats were seropositive for leptospirosis.
- Seropositive goats showed significant decreases in packed cell volume, hemoglobin, and total protein.
- Elevated alanine aminotransferase, aspartate aminotransferase, and total bilirubin levels indicated hepatic damage.
Conclusions:
- Hematobiochemical alterations in seropositive goats are indicative of liver damage.
- These findings aid in the diagnosis and therapeutic management of leptospirosis in goats.
- Urinalysis and dark field microscopy did not reveal specific diagnostic changes.
