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Related Experiment Video

Updated: Mar 22, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
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Peripherally inserted central catheters optimize nutrient intake in moderately preterm infants.

Anne L Smazal1, Anne B Kavars2, Susan J Carlson2

  • 1Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.

Pediatric Research
|April 9, 2016
PubMed
Summary
This summary is machine-generated.

Peripherally inserted central catheter (PICC) lines improve nutrient delivery for moderately preterm infants. This leads to significantly better weight gain by discharge, supporting enhanced growth in this vulnerable population.

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Area of Science:

  • Neonatal Nutrition
  • Pediatric Gastroenterology
  • Infant Growth and Development

Background:

  • Nutritional support practices vary for moderately preterm infants (32-34 weeks gestation).
  • Very preterm infants (<32 weeks gestation) routinely receive intensive nutritional support via central lines.

Purpose of the Study:

  • To evaluate the impact of peripherally inserted central catheter (PICC) use on nutrient delivery within the first two weeks of life.
  • To assess the effect of PICC-delivered nutrition on growth outcomes in moderately preterm infants by hospital discharge.

Main Methods:

  • Retrospective analysis of 187 infants born between 32 and 34 6/7 weeks gestation.
  • Comparison of nutrient intake and weight gain between infants receiving nutrition via PICC and those who did not.
  • Data collection included feedings, weights, and PICC placement records.

Main Results:

  • Infants receiving nutrition via PICC had significantly higher kilocalorie and protein intake in the first week of life.
  • PICC group infants received an average of 17.6 more kcal/day and 1.2 more g protein/kg/day.
  • By discharge, infants in the PICC group showed significantly greater weight gain (302g more).

Conclusions:

  • Peripherally inserted central catheter (PICC) lines facilitate superior nutrient delivery in moderately preterm infants.
  • PICC use is associated with enhanced growth and weight gain in this population.
  • This method supports improved nutritional outcomes for infants born between 32-34 weeks gestation.