Delayed neurologic display in murine typhus. Report of two cases

Two cases of murine typhus with prolonged neurologic manifestations appearing after the febrile stage of the illness are described. One patient had behavioral and memory disturbances for almost 18 months after defervescence, which terminated gradually without specific therapy. The second patient had similar manifestations over a period of weeks that rapidly resolved after tetracycline therapy. Such phenomena were not previously described in the literature, as far as we know, although similar manifestations were noted in Rocky Mountain spotted fever.