Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

830
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
830

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation.

Science (New York, N.Y.)·2026
Same author

Melanoma: Cutaneous, Version 2.2026, NCCN Clinical Practice Guidelines In Oncology.

Journal of the National Comprehensive Cancer Network : JNCCN·2026
Same author

Sentinel lymph node biopsy utilization and positivity in veterans with cutaneous melanoma: A comparative analysis of the VA Cancer Registry and the SEER Program.

Journal of the American Academy of Dermatology·2026
Same author

Correction: Oregon primary care providers as a frontline defense in the War on Melanoma™: improving access to melanoma education.

Frontiers in medicine·2026
Same author

Correction: Melanoma toolkit for early detection for primary care clinicians: a 1-year follow-up on outcomes.

Frontiers in medicine·2026
Same author

Single-cell spatial transcriptomic analysis of human skin anatomy.

Nature genetics·2026

Related Experiment Video

Updated: Mar 22, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

16.8K

Molecular Profiling in Cutaneous Melanoma.

Andrew L Ji1,2, Christopher K Bichakjian3, Susan M Swetter1,2

  • 1VA Palo Alto Health Care System, Dermatology Service, Palo Alto, Stanford, California

Journal of the National Comprehensive Cancer Network : JNCCN
|April 10, 2016
PubMed
Summary

Molecular profiling offers new ways to diagnose and predict melanoma outcomes. These advanced techniques aim to improve patient care by guiding treatment decisions for better melanoma management.

More Related Videos

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
07:41

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

3.0K
DNA-barcode-based Multiplex Immunofluorescence Imaging to Analyze FFPE Specimens from Genetically Reprogrammed Murine Melanoma
09:58

DNA-barcode-based Multiplex Immunofluorescence Imaging to Analyze FFPE Specimens from Genetically Reprogrammed Murine Melanoma

Published on: June 6, 2025

1.2K

Related Experiment Videos

Last Updated: Mar 22, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

16.8K
A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
07:41

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

3.0K
DNA-barcode-based Multiplex Immunofluorescence Imaging to Analyze FFPE Specimens from Genetically Reprogrammed Murine Melanoma
09:58

DNA-barcode-based Multiplex Immunofluorescence Imaging to Analyze FFPE Specimens from Genetically Reprogrammed Murine Melanoma

Published on: June 6, 2025

1.2K

Area of Science:

  • Oncology
  • Dermatology
  • Molecular Biology

Background:

  • Molecular profiling of malignant tumors is increasingly important in oncology.
  • Melanoma research is exploring various molecular techniques to enhance diagnosis and prognosis.
  • Current clinical and histopathologic parameters for melanoma have limitations.

Purpose of the Study:

  • To review available molecular diagnostic and prognostic techniques for melanoma.
  • To evaluate the potential clinical utility of these molecular methods.
  • To highlight how molecular tests can improve melanoma patient management.

Main Methods:

  • Review of current literature on molecular techniques in melanoma.
  • Analysis of diagnostic and prognostic molecular assays.
  • Evaluation of clinical applicability and potential impact on patient outcomes.

Main Results:

  • Several molecular techniques show promise for melanoma diagnosis and prognosis.
  • These methods could potentially refine patient stratification for therapy.
  • Early application of reliable molecular tests may reduce melanoma morbidity and mortality.

Conclusions:

  • Molecular profiling represents a significant advancement in melanoma diagnostics and prognostics.
  • Further integration of molecular techniques into clinical practice is warranted.
  • Personalized treatment strategies for melanoma can be enhanced through molecular insights.