Amperometric ascorbic acid sensor based on doped ferrites nanoparticles modified glassy carbon paste electrode.

Area of Science:

• Electrochemistry
• Materials Science
• Analytical Chemistry

Background:

• Ascorbic acid quantification is crucial in physiological studies.
• Conventional methods for ascorbic acid analysis are often time-consuming and expensive.
• Development of novel electrochemical sensors is needed for efficient detection.

Purpose of the Study:

• To construct a novel electrochemical sensor for ascorbic acid quantification.
• To utilize cobalt and nickel ferrites for modifying a glassy carbon paste electrode (GCPE).
• To evaluate the sensor's performance under physiological conditions.

Main Methods:

• Synthesis of cobalt and nickel ferrites using microwave and ultrasound assistance.
• Characterization of synthesized materials using SEM, FTIR, and XRPD.
• Modification of GCPE with ferrite nanoparticles and amperometric detection of ascorbic acid.

Main Results:

• Ferrite nanoparticle modification significantly improved the analytical performance of GCPE.
• The cobalt ferrite-modified GCPE (CoFeGCPE) exhibited superior characteristics for ascorbic acid sensing.
• The sensor achieved a limit of detection (LOD) of 0.0270 mg/L within a linear range of 0.1758 to 2.6010 mg/L.

Conclusions:

• The developed CoFeGCPE sensor provides a sensitive and reliable method for ascorbic acid quantification.
• This novel sensor demonstrates potential as a cost-effective and efficient alternative to conventional methods.
• The sensor's successful application in practical analysis highlights its utility in physiological studies.