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Migraine-tic syndrome: Two further case reports
Stephan Hinze1, Paul Davies2, Tess Astbury2
11 Department of Neurology, Great Western Hospital, Swindon, UK.
Cephalalgia : an International Journal of Headache
|April 10, 2016
Summary
Migraine-tic syndrome, characterized by co-occurring trigeminal neuralgia and migraine, is further supported by two new cases. These findings suggest a shared pathophysiological pathway for both headache disorders.
Area of Science:
- Neurology
- Headache Medicine
Background:
- Migraine-tic syndrome, an overlap condition, was initially described in 2004.
- This syndrome involves concurrent symptoms of trigeminal neuralgia and migraine.
Observation:
- Two new cases of migraine-tic syndrome are presented.
- Case 1: Trigeminal neuralgia preceded migraine; both responded to sumatriptan.
- Case 2: Trigeminal neuralgia followed migraine; treated with baclofen and amitriptyline.
Findings:
- These cases provide additional evidence for the existence of migraine-tic syndrome.
- The study suggests a potential common pathophysiological mechanism linking trigeminal neuralgia and migraine.
Implications:
- Further research into the shared pathways of these headache disorders is warranted.
- Understanding this overlap may lead to improved diagnostic and therapeutic strategies for patients with complex headache presentations.

