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Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

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Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
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Hypoxia01:23

Hypoxia

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Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
2.5K
Oxygen Transport in the Blood01:27

Oxygen Transport in the Blood

8.1K
Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...
8.1K
Pneumothorax-I01:26

Pneumothorax-I

1.9K
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
1.9K
Oxygen Delivering System III: Tracheostomy and T-piece01:23

Oxygen Delivering System III: Tracheostomy and T-piece

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Oxygen delivery is critical in clinical care, especially for patients with respiratory disorders or those undergoing surgical procedures. Various systems, such as tracheostomy and the T-piece, deliver oxygen to the lungs, ensuring adequate arterial oxygenation.
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
7.9K
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

3.1K
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
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Assessment of the interaction of hyperbaric N2, CO2, and O2 on psychomotor performance in divers.

Journal of applied physiology (Bethesda, Md. : 1985)·2016
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Risk factors for immersion pulmonary edema: hyperoxia does not attenuate pulmonary hypertension associated with cold water-immersed prone exercise at 4.7 ATA.

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Triage and emergency evacuation of recreational divers: a case series analysis.

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Effects of head and body cooling on hemodynamics during immersed prone exercise at 1 ATA.

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Related Experiment Video

Updated: Mar 22, 2026

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head
05:55

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head

Published on: September 27, 2024

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Hyperbaric oxygen therapy and osteonecrosis.

P Ceponis1,2, C Keilman1, C Guerry1

  • 1Hyperbaric Division, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.

Oral Diseases
|April 11, 2016
PubMed
Summary
This summary is machine-generated.

Osteonecrosis of the jaw, a condition linked to radiation, medication, or infection, benefits from multimodal therapy. This review examines adjunctive hyperbaric oxygen therapy as a treatment option.

Keywords:
hyperbaric oxygenosteonecrosistherapieswound healing

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Hyperbaric Medicine
  • Oncology

Background:

  • Osteonecrosis of the jaw (ONJ) is a serious condition with diverse etiologies including radiation, medication, and infection.
  • Current treatment paradigms emphasize a multimodal approach, integrating surgical interventions with adjuvant therapies.
  • Hyperbaric oxygen therapy (HBOT) is increasingly explored as a potential adjunctive treatment for ONJ.

Purpose of the Study:

  • To review the current evidence on the use of adjunctive hyperbaric oxygen therapy for osteonecrosis of the jaw.
  • To discuss the basic and clinical science underpinning HBOT's efficacy in ONJ.
  • To explore controversies and economic factors associated with HBOT for ONJ.

Main Methods:

  • Systematic review of existing literature.
  • Analysis of basic science research on HBOT mechanisms.
  • Evaluation of clinical trial data and case studies.
  • Discussion of expert opinions and economic analyses.

Main Results:

  • HBOT demonstrates potential benefits in managing ONJ by promoting tissue healing and reducing inflammation.
  • Evidence supports HBOT's role in specific patient populations, particularly those with medication-related ONJ.
  • Controversies remain regarding optimal HBOT protocols and patient selection criteria.

Conclusions:

  • Adjunctive hyperbaric oxygen therapy represents a promising component of multimodal treatment for osteonecrosis of the jaw.
  • Further research is warranted to refine HBOT protocols and solidify its place in clinical guidelines.
  • The integration of HBOT requires careful consideration of its benefits, risks, and economic implications.