Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Demonstration of partially transparent thick metallic sodium in the vacuum ultraviolet spectral range: comment.

Optics express·2026

Same author

Tartrate-Assisted Ionic Layer Epitaxy for General Synthesis of 2D Nanostructures.

Small methods·2025

Same author

Simulation study of the performance of neural network-enhanced PACBED for characterizing atomic-scale deformations in 2D van der Waals materials.

Ultramicroscopy·2025

Same author

SuperSalt: equivariant neural network force fields for multicomponent molten salts system.

Nature communications·2025

Same author

Tradipitant Effective in the Reduction of Vomiting Associated with Motion Sickness Across Varied Sea Conditions (S3.003).

Neurology·2025

Same author

Ultranarrow Semiconductor WS<sub>2</sub> Nanoribbon Field-Effect Transistors.

Nano letters·2025

Same journal

Engineered Young Brown Adipose Tissue-Derived Exosomes Alleviate Radiation-Induced Lung Injury by Promoting G Protein-Coupled Receptor 183 Ubiquitination.

ACS nano·2026

Same journal

Pore Geometry-Driven Capture of Trace Aromatic Volatile Organic Compounds in Al-Based MOFs.

ACS nano·2026

Same journal

Dual-Bridged Porphyrin-Based Covalent Organic Framework with Integrated Specific Fluorescent Recognition and Cooperative Adsorption Capabilities.

ACS nano·2026

Same journal

Split-Gate Memtransistors for Energy-Efficient Adaptive Reinforcement Learning.

ACS nano·2026

Same journal

Interface Coordination Nucleation of Copper Nanoclusters on Covalent Organic Frameworks for Electrocatalytic Ammonia Synthesis.

ACS nano·2026

Same journal

High-Performance Near-Infrared Quantum Emission from Color Centers in hBN.

ACS nano·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 22, 2026

Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering

Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering

Published on: November 5, 2018

Integrated Computational and Experimental Structure Refinement for Nanoparticles.

Min Yu¹, Andrew B Yankovich¹, Amy Kaczmarowski¹

¹Department of Materials Science and Engineering, University of Wisconsin-Madison , Madison, Wisconsin 53706, United States.

|April 12, 2016

Summary

This summary is machine-generated.

We developed a new computational tool to determine nanoparticle atomic structures. This method refines 3D models using genetic algorithms and experimental data for accurate property identification.

Keywords:

genetic algorithm nanoclusters nanoparticles scanning transmission electron microscopy structure optimization

More Related Videos

A Robust Single-Particle Cryo-Electron Microscopy cryo-EM Processing Workflow with cryoSPARC, RELION, and Scipion

A Robust Single-Particle Cryo-Electron Microscopy cryo-EM Processing Workflow with cryoSPARC, RELION, and Scipion

Published on: January 31, 2022

High-resolution Single Particle Analysis from Electron Cryo-microscopy Images Using SPHIRE

High-resolution Single Particle Analysis from Electron Cryo-microscopy Images Using SPHIRE

Published on: May 16, 2017

Related Experiment Videos

Last Updated: Mar 22, 2026

Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering

Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering

Published on: November 5, 2018

A Robust Single-Particle Cryo-Electron Microscopy cryo-EM Processing Workflow with cryoSPARC, RELION, and Scipion

A Robust Single-Particle Cryo-Electron Microscopy cryo-EM Processing Workflow with cryoSPARC, RELION, and Scipion

Published on: January 31, 2022

High-resolution Single Particle Analysis from Electron Cryo-microscopy Images Using SPHIRE

High-resolution Single Particle Analysis from Electron Cryo-microscopy Images Using SPHIRE

Published on: May 16, 2017

Area of Science:

Materials Science
Computational Chemistry
Nanotechnology

Background:

Understanding nanoparticle properties relies heavily on knowing their 3D atomic structure.
Experimental techniques like scanning transmission electron microscopy (STEM) provide crucial data but require sophisticated analysis for 3D reconstruction.

Purpose of the Study:

To present an integrated computational tool for refining nanoparticle 3D atomic structures.
To combine forward modeling with experimental STEM data and energy minimization for accurate structural determination.

Main Methods:

Development of a genetic algorithm (GA) optimization tool.
Integration of GA with forward modeling based on experimental STEM data.
Simultaneous minimization of nanoparticle energy during structural refinement.

Main Results:

Successful refinement of the 3D atomic structure of a gold (Au) nanoparticle containing approximately 6000 atoms.
Generation of a high-fidelity 3D structural model validated against experimental observations.

Conclusions:

The developed GA-based tool effectively refines nanoparticle 3D atomic structures.
Accurate structural models are essential for correlating nanoparticle structure with their properties.