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Updated: Nov 17, 2025

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
Published on: May 22, 2020
Imaging of Cerebrospinal Fluid Leak
Girish Bathla1, Toshio Moritani1
1Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA.
Abstract:
A cerebrospinal fluid leak from the cranial cavity requires presence of a fistulous communication between the subarachnoid and extracranial space through the skull base. Imaging plays a crucial role in identifying and characterizing the skull base defect and evaluating coexisting pathologies that may alter surgical approach. The authors discuss the epidemiology, imaging, and management of cerebrospinal fluid leak, with particular reference to the imaging modalities and findings.
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