Central Retinal Vein Occlusion Associated With Severe Vitamin D Deficiency

Central retinal vein occlusion (CRVO) is thought to occur due to thrombotic occlusion of the central retinal vein at or just posterior to the lamina cribrosa. Studies have shown that the incidence of CRVO may be higher in winter to early spring, suggesting that low vitamin D levels may play a role; however, no studies have measured vitamin D levels in patients with CRVO. In addition, there is mounting evidence that patients with vitamin D deficiency may be predisposed to thrombotic events. The authors report a case of central retinal vein occlusion associated with marked vitamin D deficiency.