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Updated: Mar 22, 2026

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis
Published on: September 10, 2014
Molecular conductance of double-stranded DNA evaluated by electrochemical capacitance spectroscopy
W C Ribeiro1, L M Gonçalves2, S Liébana3
1Instituto de Química, Universidade Estadual Paulista, (Nanobionics Research Group), CP 355, 14800-900, Araraquara, SP, Brazil.
Abstract:
Conductance was measured in two different double stranded DNA (both with 20 bases), the more conducting poly(dG)-poly(dC) (ds-DNAc) and the less conducting poly(dA)-poly(dT) (ds-DNAi), by means of Electrochemical Capacitance Spectroscopy (ECS). The use of the ECS approach, exemplified herein with DNA nanowires, is equally a suitable and time-dependent advantageous alternative for conductance measurement of molecular systems, additionally allowing better understanding of the alignment existing between molecular scale conductance and electron transfer rate.
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