Commissioning and initial experience with the first clinical gantry-mounted proton therapy system

Area of Science:

• Medical Physics
• Radiation Oncology

Background:

• Proton therapy offers precise radiation delivery.
• Advancements in technology are crucial for expanding its clinical use.

Purpose of the Study:

• To detail the commissioning and initial clinical use of the Mevion S250 proton therapy system.
• To evaluate the system's performance and suitability for patient treatment.

Main Methods:

• Comprehensive commissioning including CT calibration and beam data acquisition.
• Dosimetric commissioning and validation using phantoms for various anatomical sites.
• Evaluation of the image guidance system's localization accuracy.

Main Results:

• Successful commissioning of the Mevion S250 system.
• Positive validation results from the Imaging and Radiation Oncology Core credentialing.
• The system demonstrated reliable operation and accurate image guidance.

Conclusions:

• The Mevion S250 proton therapy system is a well-commissioned and effective platform.
• Initial clinical experience indicates its suitability for treating various diseases with protons.