Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intensive Rehabilitation With Adjunctive Bilateral Anodal tDCS in Post-Stroke Dysphagia: A Multicenter Randomized Controlled Trial.

European journal of neurology·2026
Same author

Real-world chronic recordings from implantable adaptive deep brain stimulation systems for Parkinson's disease motor state classification.

Frontiers in bioinformatics·2026
Same author

Psychosocial and body image alterations associated with focal dystonia.

Journal of neural transmission (Vienna, Austria : 1996)·2026
Same author

Pushing athletic performance boundaries with anodal transcranial direct current stimulation: an exploratory, pilot, randomized controlled study on strength and inflammation in elite weightlifters.

BMC sports science, medicine & rehabilitation·2026
Same author

Effects of Transcutaneous Spinal Direct Current Stimulation on Cognitive and Psychological Outcomes in Multiple Sclerosis: A Preliminary Case Series.

Biomedicines·2026
Same author

Reduced Childhood Outdoor Exposure Raises Pediatric Multiple Sclerosis (PedMS) Risk.

Neurology and therapy·2026
Same journal

Adverse event trajectories and treatment discontinuation in advanced Parkinson's disease treated with levodopa/carbidopa intestinal gel.

Parkinsonism & related disorders·2026
Same journal

GBA1 variants and dopaminergic imaging in essential tremor with atypical features: A comparative study with Parkinson's disease.

Parkinsonism & related disorders·2026
Same journal

Cerebellum crus II cortical thickness as a cognitive brain reserve in Parkinson's disease.

Parkinsonism & related disorders·2026
Same journal

Serious games and virtual reality in Parkinson's disease rehabilitation: A systematic review of randomized controlled trials.

Parkinsonism & related disorders·2026
Same journal

Respiratory-swallow training in Parkinson's disease: Effects of a single session on swallowing safety and efficiency with exploratory comparisons of biofeedback.

Parkinsonism & related disorders·2026
Same journal

Levodopa responsive childhood-onset generalized dystonia with diaphragmatic involvement associated with an SPTBN2 variant.

Parkinsonism & related disorders·2026
See all related articles

Related Experiment Video

Updated: Mar 22, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

23.3K

The adaptive deep brain stimulation challenge.

Mattia Arlotti1, Manuela Rosa2, Sara Marceglia3

  • 1Clinical Center for Neurostimulation, Neurotechnology, and Movement Disorders, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Electronics, Computer Science and Systems, University of Bologna, Cesena, Italy.

Parkinsonism & Related Disorders
|April 16, 2016
PubMed
Summary
This summary is machine-generated.

Adaptive deep brain stimulation (aDBS) offers improved Parkinson's Disease (PD) treatment by adjusting stimulation in real-time. Key challenges involve selecting the right control variable and algorithm for successful clinical translation.

Keywords:
Adaptive deep brain stimulationBasal ganglia local field potentialsControl variableParkinson's disease

More Related Videos

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

13.6K
Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

9.4K

Related Experiment Videos

Last Updated: Mar 22, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

23.3K
Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

13.6K
Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
14:14

Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

Published on: August 12, 2018

9.4K

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Neurological Disorders

Background:

  • Conventional deep brain stimulation (cDBS) for Parkinson's Disease (PD) has limitations in clinical outcomes.
  • There is a growing need for advanced therapeutic solutions to enhance DBS efficacy.

Purpose of the Study:

  • To review current adaptive deep brain stimulation (aDBS) systems.
  • To analyze the critical role of control variable and algorithm selection in aDBS.
  • To provide an overview of aDBS clinical translation pathways, including benefits and challenges.

Main Methods:

  • Review of existing literature on adaptive deep brain stimulation (aDBS) systems.
  • Focus on the selection, advantages, and disadvantages of different control variables.
  • Analysis of system design, technological limitations, target symptoms, and surgical considerations.

Main Results:

  • aDBS systems vary significantly in control variable and algorithm choices.
  • Different approaches present unique advantages and drawbacks impacting system design and application.
  • Technological limits and patient-specific factors influence the feasibility of aDBS implementation.

Conclusions:

  • The choice of control variable and algorithm is central to aDBS design and efficacy.
  • Successful clinical translation of aDBS requires addressing technical and patient-specific challenges.
  • Further research is needed to overcome limitations and optimize aDBS for Parkinson's Disease treatment.