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Updated: Mar 22, 2026

Clinical-oriented Three-dimensional Gait Analysis Method for Evaluating Gait Disorder
Published on: March 4, 2018
A principal component analysis approach to correcting the knee flexion axis during gait
Elisabeth Jensen1, Vipul Lugade2, Jeremy Crenshaw3
1Mayo Graduate School, Biomedical Engineering and Physiology Track, Mayo Clinic, Rochester, MN 55905, USA; Motion Analysis Laboratory, Division of Orthopedic Research, Mayo Clinic, Charlton North L-110L, Rochester, MN 55905, USA.
A new principal component analysis (PCA)-based algorithm accurately corrects knee flexion axis errors caused by marker misplacement. This method enhances the precision and certainty of knee kinematics in gait analysis.
Area of Science:
- Biomechanics
- Gait Analysis
- Orthopedic Surgery
Background:
- Accurate knee flexion axis identification is crucial for tibial and femoral derotation osteotomies.
- Marker misplacement during gait analysis frequently leads to errors in knee flexion axis identification.
Purpose of the Study:
- To develop an efficient algorithm for post-hoc correction of knee flexion axis errors.
- To evaluate the efficacy of the developed algorithm against existing methods.
Main Methods:
- Gait data were collected from twelve healthy subjects with both standard and intentionally misplaced lateral knee markers.
- A principal component analysis (PCA)-based algorithm was developed for error correction.
- Efficacy was assessed by quantifying reductions in knee angle errors (crosstalk and rotation offset).
Main Results:
- The PCA-based algorithm significantly reduced crosstalk error (r(2)) (p<0.001).
- It improved the certainty of knee kinematics, with knee rotation converging to 11.9±8.0° external rotation.
- Precision was enhanced, reducing the within-subject standard deviation of hip rotation offset error from 13.5±1.5° to 0.7±0.2° (p<0.001).
Conclusions:
- The PCA-based algorithm effectively corrects knee flexion axis errors caused by marker misplacement.
- This method offers improved precision and certainty in gait analysis for knee kinematics.
- Its performance is comparable to established methods and superior to the null space algorithm.
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