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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Related Experiment Video

Updated: Mar 22, 2026

Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia

Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia

Published on: July 2, 2013

Imaging effects related to language improvements by rTMS.

Wolf-Dieter Heiss

Restorative Neurology and Neuroscience

|April 16, 2016

Summary

Non-invasive brain stimulation (NIBS) can help stroke recovery by modulating brain networks. Inhibitory NIBS targeting the right hemisphere improved language function in post-stroke aphasia patients, showing promise for rehabilitation.

Keywords:

Non-invasive brain stimulation aphasia positron emission tomography repetitive transcranial magnetic stimulation stroke

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Last Updated: Mar 22, 2026

Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia

Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia

Published on: July 2, 2013

Neuronavigation-guided Repetitive Transcranial Magnetic Stimulation for Aphasia

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Published on: May 6, 2016

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Published on: March 24, 2023

Area of Science:

Neuroscience
Neurology
Rehabilitation Medicine

Background:

Focal brain lesions cause functional deficits, with recovery relying on neural network reorganization.
Functional neuroimaging, like PET, visualizes network changes and recovery after stroke.
The unaffected hemisphere can inhibit recovery, a phenomenon known as transcallosal inhibition.

Purpose of the Study:

To investigate the potential of non-invasive brain stimulation (NIBS) to promote adaptive cortical reorganization after stroke.
To explore the efficacy of NIBS in modulating functional networks and improving outcomes in post-stroke aphasia.

Main Methods:

Utilized functional imaging modalities such as positron emission tomography (PET) for longitudinal assessments.
Employed non-invasive brain stimulation (NIBS), specifically inhibitory low-frequency repetitive transcranial magnetic stimulation (rTMS), targeting the right inferior frontal gyrus.
Conducted controlled randomized studies with sham stimulation and correlated PET activation patterns with aphasia test performance.

Main Results:

Inhibitory rTMS over the right inferior frontal gyrus induced a shift in activation patterns towards the dominant hemisphere.
This shift in neural activity correlated with improved performance in aphasia tests.
PET imaging demonstrated changes in functional network reorganization following NIBS intervention.

Conclusions:

Non-invasive brain stimulation (NIBS) shows potential as an adjunct treatment to enhance stroke rehabilitation.
Modulating interhemispheric interactions via NIBS can facilitate recovery of functions like language after stroke.
Further controlled studies are warranted to establish NIBS as a standard treatment strategy for post-stroke deficits.