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Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy
Published on: November 1, 2011
Complete Genome Sequence of Rift Valley Fever Virus Strain Lunyo
Sarah Lumley1, Daniel L Horton2, Denise A Marston3
1Virology and Pathogenesis Group, Microbiology Services Division, Public Health England, Wiltshire, United Kingdom Department of Pathology and Infectious Disease, School of Veterinary Medicine, University of Surrey, Guildford, United Kingdom Wildlife Zoonoses and Vector-Borne Diseases Research Group, Animal and Plant Health Agency, Addlestone, Surrey, United Kingdom sarah.lumley@phe.gov.uk.
Abstract:
Using next-generation sequencing technologies, the first complete genome sequence of Rift Valley fever virus strain Lunyo is reported here. Originally reported as an attenuated antigenic variant strain from Uganda, genomic sequence analysis shows that Lunyo clusters together with other Ugandan isolates.
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