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The Mammary Glands01:12

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The female breast is a hemispheric projection of variable size positioned anterior to the pectoralis major and serratus anterior muscles. A fascia layer composed of dense, irregular connective tissue connects it to these muscles.
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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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Updated: Mar 22, 2026

Intraductal Delivery to the Rabbit Mammary Gland
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Phyllodes Tumor in a Lactating Breast.

Sudha S Murthy1, K V V N Raju2, Haripreetha G Nair3

  • 1Senior Consultant, Department of Pathology Laboratory Medicine, Basavatarakam Indo-American Cancer Hospital and Research Institute, Hyderabad, Telangana, India.

Clinical Medicine Insights. Pathology
|April 16, 2016
PubMed
Summary
This summary is machine-generated.

This case highlights a rare phyllodes tumor in a lactating mother. Early diagnosis via biopsy is crucial for appropriate treatment and management of this benign breast tumor.

Keywords:
benign phyllodes tumorlactating breaststromal proliferation

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Area of Science:

  • Oncology
  • Pathology
  • Reproductive Medicine

Background:

  • Phyllodes tumors are rare breast neoplasms, accounting for a small percentage of primary breast tumors.
  • Their occurrence during pregnancy and lactation is exceptionally uncommon, posing diagnostic challenges.

Observation:

  • A 25-year-old lactating woman presented with a palpable breast lump.
  • Initial core needle biopsy suggested phyllodes tumor with lactational changes.

Findings:

  • Wide local excision confirmed a benign phyllodes tumor with concurrent lactational changes.
  • Diagnostic hallmarks include a circumscribed lesion with a leaf-like fibroepithelial structure and stromal proliferation, even without mitotic figures.

Implications:

  • Benign phyllodes tumors have a propensity for recurrence, necessitating wide excision and diligent follow-up.
  • Accurate identification on limited biopsies is critical as it influences therapeutic strategies.