Related Experiment Video
Updated: Mar 22, 2026
05:27
Laparoscopic Anatomical Hepatectomy Using Takasaki's Approach and Indocyanine Green Fluorescence Navigation
Published on: May 16, 2025
1.0K
BioGlue for traumatic liver laceration
Edward Daniele1, Sharmila Dissanaike1
1Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX 79416, United States.
International Journal of Surgery Case Reports
|April 17, 2016
Summary
This case study highlights the successful delayed repair of a Grade 4 blunt liver injury using Bioglue after initial packing and endoscopic retrograde cholangiopancreatography (ERCP) stenting for bile leak management.
Area of Science:
- Trauma Surgery
- Hepatobiliary Surgery
- Surgical Innovation
Background:
- Non-operative management is standard for blunt liver injuries.
- Hemostatic agents offer adjunct treatment for bile leaks, particularly in surgical cases involving biloma drainage.
Purpose of the Study:
- To present a case of delayed repair for a Grade 4 liver laceration with bile leak.
- To evaluate the use of a hemostatic biologic agent (Bioglue) in managing traumatic liver injuries with associated bile extravasation.
Main Methods:
- A 31-year-old female with Grade 4 liver injury underwent exploratory laparotomy with hemostatic mesh packing.
- Post-discharge, a bile leak was identified, managed with ERCP and stenting.
- A subsequent laparotomy allowed for direct application of Bioglue to the liver laceration.
Main Results:
- The patient developed a bile leak after initial management.
- Endoscopic retrograde cholangiopancreatography (ERCP) with stenting successfully diverted bile flow.
- Bioglue was effectively used to seal the liver laceration during a delayed laparotomy.
Conclusions:
- Laparotomy was essential for managing the high-volume biloma.
- Bioglue served as a valuable adjunct for sealing the liver laceration and controlling bile extravasation.
- This case demonstrates a novel and safe approach for delayed repair of traumatic liver lacerations.
