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Odontogenic carcinoma with sarcomatous proliferation. A case report
T Yoshida1, S Shingaki, T Nakajima
1First Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Niigata University.
Summary
This case study details an unusual odontogenic carcinoma of the mandible with sarcomatous features. Successful treatment involved surgical resection and neck dissection for this rare mandibular tumor.
Area of Science:
- Oral pathology
- Surgical oncology
- Head and neck cancer
Background:
- Odontogenic carcinomas are rare malignant tumors arising from odontogenic epithelium.
- The World Health Organization (WHO) classification categorizes odontogenic carcinomas into specific entities.
- This report presents a unique case that challenges existing classifications.
Observation:
- A patient presented with an aggressive odontogenic carcinoma of the mandible.
- The tumor exhibited invasive bone destruction and soft tissue extension.
- Histopathological examination revealed ameloblastomatous features and a predominant proliferation of epithelial cells in a collagenous stroma.
Findings:
- The intrabony lesion showed epithelial cells in strands and networks within a stroma.
- The extrabony component displayed tumor cells with a fibroblastic appearance.
- The observed features did not align with any of the established WHO categories of odontogenic carcinoma.
Implications:
- This case highlights the diverse histopathological presentations of odontogenic carcinomas.
- It suggests the need for potential revision or expansion of current classifications.
- Understanding such unusual presentations is crucial for accurate diagnosis and effective treatment planning in head and neck oncology.